Inside the research

Charles River Laboratories International, Inc.

CRL Research profile · latest available data

Price overview

$292.84

▼ -1.60 (-0.5%)

52w hi$298.58
52w lo$145.57
Vol838.30K
As of25 Sep 2026

The Verdict

Hold

Our score +0.20

Short+0.47
Medium+0.28
Long-0.49

computed 2026-09-27

Key fundamentals

Charles River Laboratories International, Inc.

Healthcare · Diagnostics & Research

Market cap$14.11B
Enterprise value$16.87B
Forward P/E23.04x
EV / EBITDA19.87x
P / S (ttm)3.50x
Profit margin-6.0%
Return on equity-7.5%
Revenue growth-2.7%
Debt / equity105.05

Layer Breakdown

LayerRawContribution
Fundamental-0.11
Sector+0.08
Technical+0.30
Earnings+0.00
Sentiment+0.00

macro × 1.00 · 2026-09-27

Business overview

Charles River Laboratories International, Inc. provides drug discovery, non-clinical development, and safety testing services in the United States, Europe, Canada, the Asia Pacific, and internationally. The Research Models and Services segment produces and sells rodents, and purpose-bred rats and mice for use by researchers. This segment also provides a range of services to assist its clients in supporting the use of research models in research and screening pre-clinical drug candidates, including genetically engineered models and services, insourcing solutions, and research animal diagnostic services; and engages in development and production of cell therapies. The Discovery and Safety Assessment segment offers in vitro and in vivo discovery services for the discovery, development, and safety testing of novel drugs, molecule compounds, oligonucleotides, and biotherapeutics, and antibodies through delivery of preclinical drug and therapeutic candidates ready for safety assessment; safety assessment services, such as toxicology, pathology, safety pharmacology, bioanalysis, drug metabolism, and pharmacokinetics services; and vivarium space services. The Manufacturing Solutions segment provides in vitro methods for conventional and rapid quality control testing of sterile and non-sterile pharmaceuticals and consumer products; offers specialized testing of biologics that are outsourced by pharmaceutical and biotechnology companies; and contract development and manufacturing products and services. The company has strategic collaborations with Parker Institute for Cancer Immunotherapy and Children's Hospital Los Angeles across its contract development and manufacturing organization; and Medigen Vaccine Biologics Corp for developing next-generation multivalent enterovirus vaccine, enhance global regulatory readiness, and support IND-enabling non-clinical studies. Additionally, it has a strategic alliance with Francis Crick Institute (Crick), Inc. for the development of Antibody-Drug Conjugate (ADC) drug discovery and development. Charles River Laboratories International, Inc. was founded in 1947 and is headquartered in Wilmington, Massachusetts.

United States · www.criver.com

Risk Metrics

Beta vs SPX1.36
Corr SPX0.43
Annual vol50.3%
Annual ret+30.6%
Sharpe0.61
Max DD-54.8%

Window: 504 trading days (504 obs)

Analyst Coverage

Mean PT$209.00
High / Low$265.00 / $135.00
Median$220.00
Analysts15
Strong Buy2
Buy10
Hold4
Sell0
Strong Sell1

Recent rating actions

2026-05-08Evercore ISI Group→ Outperform
2026-05-08Barclays→ Overweight
2026-04-14Barclays→ Overweight
2026-04-13JP Morgan→ Neutral
2026-02-25UBS→ Neutral
2026-02-20TD Cowen→ Buy

Material Events

DateEvent8-K
2026-08-05Earnings Release, Exhibitsread
2026-05-11Officer / Director Change, Shareholder Vote…read
2026-05-07Earnings Release, Exhibitsread
2026-02-25Reg FD Disclosureread
2026-02-18Officer / Director Change, Exhibitsread
2026-02-18Earnings Release, Exhibitsread
2026-01-13Earnings Release, Reg FD Disclosureread
2026-01-09Officer / Director Changeread
2025-12-03Reg FD Disclosureread
2025-11-17Other Material Eventread
2025-11-05Earnings Release, Exhibitsread
2025-09-16Officer / Director Change, Reg FD Disclosure…read

Insider Trades

DateInsiderRoleActionSharesValue
2026-08-11Parisotto Shannon MCEVP, Disc & Safety AssesOption exercise3.71K$667.26K
2026-08-11Girshick BirgitChief Executive OfficerSell6.50K$1.82M
2026-08-11Girshick BirgitChief Executive OfficerOption exercise6.50K$1.17M
2026-08-11Parisotto Shannon MCEVP, Disc & Safety AssesSell3.71K$1.04M
2026-08-10LaPlume Joseph WEVP, Corp Strategy & DeveGift257—
2026-08-10FOSTER JAMES COption exercise28.73K$5.16M
2026-08-10FOSTER JAMES CSell28.73K$7.90M
2026-08-06Knell Michael GunnarSVP, Finance and CAOSell810$211.77K
2026-08-06Knell Michael GunnarSVP, Finance and CAOSell901$234.83K
2026-08-06Knell Michael GunnarSVP, Finance and CAOSell1.27K$330.06K

Flow & Concentration

Insider 180d net-$31.77M
Insider buys / sells0 / 15
Insider biasSellers
13F holders0
Top-5 share0.0%
HHI0 (—)

SEC Filings

DateFormDoc
2026-08-134view
2026-08-134view
2026-08-114view
2026-08-114view
2026-08-104view
2026-08-104view
2026-08-064view
2026-08-0510-Qview
2026-08-058-Kview
2026-07-014view
2026-06-084view
2026-06-084view
2026-06-084view
2026-06-034view
2026-06-024view

The Long Run

FY 2010–2025 · 16 years

LineLatestCAGRTrend
Revenue$4.05B+7.9%
Gross profit$211.78M+12.8%
Operating income$617.26M+9.0%
Net income$22.20M-16.0%
Cash from ops$737.65M+10.8%

Indices

S&P 500

Recent Sessions

DateOpenHighLowCloseVol
Sep 25$293.19$295.23$287.23$292.84838.30K
Sep 24$277.00$298.40$276.95$294.441.59M
Sep 23$283.85$291.09$276.64$277.331.59M
Sep 22$280.19$290.11$277.41$285.111.14M
Sep 21$279.37$281.63$275.88$279.01952.90K

Understand the score. Research layers are inputs to a model, and the available data has limits.

Read the methodology →