Inside the research
Charles River Laboratories International, Inc.
CRL Research profile · latest available data
Price overview
$292.84
▼ -1.60 (-0.5%)
| 52w hi | $298.58 |
|---|---|
| 52w lo | $145.57 |
| Vol | 838.30K |
| As of | 25 Sep 2026 |
The Verdict
Our score +0.20
| Short | +0.47 |
|---|---|
| Medium | +0.28 |
| Long | -0.49 |
computed 2026-09-27
Key fundamentals
Charles River Laboratories International, Inc.
Healthcare · Diagnostics & Research
| Market cap | $14.11B |
|---|---|
| Enterprise value | $16.87B |
| Forward P/E | 23.04x |
| EV / EBITDA | 19.87x |
| P / S (ttm) | 3.50x |
| Profit margin | -6.0% |
| Return on equity | -7.5% |
| Revenue growth | -2.7% |
| Debt / equity | 105.05 |
Layer Breakdown
| Layer | Raw | Contribution |
|---|---|---|
| Fundamental | -0.11 | |
| Sector | +0.08 | |
| Technical | +0.30 | |
| Earnings | +0.00 | |
| Sentiment | +0.00 |
macro × 1.00 · 2026-09-27
Business overview
Charles River Laboratories International, Inc. provides drug discovery, non-clinical development, and safety testing services in the United States, Europe, Canada, the Asia Pacific, and internationally. The Research Models and Services segment produces and sells rodents, and purpose-bred rats and mice for use by researchers. This segment also provides a range of services to assist its clients in supporting the use of research models in research and screening pre-clinical drug candidates, including genetically engineered models and services, insourcing solutions, and research animal diagnostic services; and engages in development and production of cell therapies. The Discovery and Safety Assessment segment offers in vitro and in vivo discovery services for the discovery, development, and safety testing of novel drugs, molecule compounds, oligonucleotides, and biotherapeutics, and antibodies through delivery of preclinical drug and therapeutic candidates ready for safety assessment; safety assessment services, such as toxicology, pathology, safety pharmacology, bioanalysis, drug metabolism, and pharmacokinetics services; and vivarium space services. The Manufacturing Solutions segment provides in vitro methods for conventional and rapid quality control testing of sterile and non-sterile pharmaceuticals and consumer products; offers specialized testing of biologics that are outsourced by pharmaceutical and biotechnology companies; and contract development and manufacturing products and services. The company has strategic collaborations with Parker Institute for Cancer Immunotherapy and Children's Hospital Los Angeles across its contract development and manufacturing organization; and Medigen Vaccine Biologics Corp for developing next-generation multivalent enterovirus vaccine, enhance global regulatory readiness, and support IND-enabling non-clinical studies. Additionally, it has a strategic alliance with Francis Crick Institute (Crick), Inc. for the development of Antibody-Drug Conjugate (ADC) drug discovery and development. Charles River Laboratories International, Inc. was founded in 1947 and is headquartered in Wilmington, Massachusetts.
Risk Metrics
| Beta vs SPX | 1.36 |
|---|---|
| Corr SPX | 0.43 |
| Annual vol | 50.3% |
| Annual ret | +30.6% |
| Sharpe | 0.61 |
| Max DD | -54.8% |
Window: 504 trading days (504 obs)
Analyst Coverage
| Mean PT | $209.00 |
|---|---|
| High / Low | $265.00 / $135.00 |
| Median | $220.00 |
| Analysts | 15 |
| Strong Buy | 2 | |
|---|---|---|
| Buy | 10 | |
| Hold | 4 | |
| Sell | 0 | |
| Strong Sell | 1 |
Recent rating actions
| 2026-05-08 | Evercore ISI Group | → Outperform |
| 2026-05-08 | Barclays | → Overweight |
| 2026-04-14 | Barclays | → Overweight |
| 2026-04-13 | JP Morgan | → Neutral |
| 2026-02-25 | UBS | → Neutral |
| 2026-02-20 | TD Cowen | → Buy |
Material Events
| Date | Event | 8-K |
|---|---|---|
| 2026-08-05 | Earnings Release, Exhibits | read |
| 2026-05-11 | Officer / Director Change, Shareholder Vote… | read |
| 2026-05-07 | Earnings Release, Exhibits | read |
| 2026-02-25 | Reg FD Disclosure | read |
| 2026-02-18 | Officer / Director Change, Exhibits | read |
| 2026-02-18 | Earnings Release, Exhibits | read |
| 2026-01-13 | Earnings Release, Reg FD Disclosure | read |
| 2026-01-09 | Officer / Director Change | read |
| 2025-12-03 | Reg FD Disclosure | read |
| 2025-11-17 | Other Material Event | read |
| 2025-11-05 | Earnings Release, Exhibits | read |
| 2025-09-16 | Officer / Director Change, Reg FD Disclosure… | read |
Insider Trades
| Date | Insider | Role | Action | Shares | Value |
|---|---|---|---|---|---|
| 2026-08-11 | Parisotto Shannon M | CEVP, Disc & Safety Asses | Option exercise | 3.71K | $667.26K |
| 2026-08-11 | Girshick Birgit | Chief Executive Officer | Sell | 6.50K | $1.82M |
| 2026-08-11 | Girshick Birgit | Chief Executive Officer | Option exercise | 6.50K | $1.17M |
| 2026-08-11 | Parisotto Shannon M | CEVP, Disc & Safety Asses | Sell | 3.71K | $1.04M |
| 2026-08-10 | LaPlume Joseph W | EVP, Corp Strategy & Deve | Gift | 257 | — |
| 2026-08-10 | FOSTER JAMES C | Option exercise | 28.73K | $5.16M | |
| 2026-08-10 | FOSTER JAMES C | Sell | 28.73K | $7.90M | |
| 2026-08-06 | Knell Michael Gunnar | SVP, Finance and CAO | Sell | 810 | $211.77K |
| 2026-08-06 | Knell Michael Gunnar | SVP, Finance and CAO | Sell | 901 | $234.83K |
| 2026-08-06 | Knell Michael Gunnar | SVP, Finance and CAO | Sell | 1.27K | $330.06K |
Flow & Concentration
| Insider 180d net | -$31.77M |
|---|---|
| Insider buys / sells | 0 / 15 |
| Insider bias | Sellers |
| 13F holders | 0 |
| Top-5 share | 0.0% |
| HHI | 0 (—) |
SEC Filings
The Long Run
FY 2010–2025 · 16 years
| Line | Latest | CAGR | Trend |
|---|---|---|---|
| Revenue | $4.05B | +7.9% | |
| Gross profit | $211.78M | +12.8% | |
| Operating income | $617.26M | +9.0% | |
| Net income | $22.20M | -16.0% | |
| Cash from ops | $737.65M | +10.8% |
Indices
Recent Sessions
| Date | Open | High | Low | Close | Vol |
|---|---|---|---|---|---|
| Sep 25 | $293.19 | $295.23 | $287.23 | $292.84 | 838.30K |
| Sep 24 | $277.00 | $298.40 | $276.95 | $294.44 | 1.59M |
| Sep 23 | $283.85 | $291.09 | $276.64 | $277.33 | 1.59M |
| Sep 22 | $280.19 | $290.11 | $277.41 | $285.11 | 1.14M |
| Sep 21 | $279.37 | $281.63 | $275.88 | $279.01 | 952.90K |
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