Inside the research

Cytokinetics, Incorporated

CYTK Research profile · latest available data

Price overview

$64.66

▼ -1.00 (-1.5%)

52w hi$87.26
52w lo$47.83
Vol1.60M
As of25 Sep 2026

The Verdict

Hold

Our score -0.45

Short-0.11
Medium-0.42
Long-1.16

computed 2026-09-27

Key fundamentals

Cytokinetics, Incorporated

Healthcare · Biotechnology

Market cap$8.99B
Enterprise value$9.25B
Forward P/E-14.52x
EV / EBITDA-13.30x
P / S (ttm)132.84x
Profit margin0.0%
Revenue growth-57.1%

Layer Breakdown

LayerRawContribution
Fundamental-0.31
Sector+0.08
Technical-0.17
Earnings+0.00
Sentiment+0.00

macro × 1.00 · 2026-09-27

Business overview

Cytokinetics, Incorporated, a biopharmaceutical company, focuses on discovering, developing, and commercializing novel muscle activators and muscle inhibitors as potential treatments for debilitating diseases in the United States. The company markets MYQORZO, a novel, oral, and small molecule cardiac myosin inhibitor for the treatment of symptomatic oHCM. It also develops Aficamten, a novel, oral, and small molecule cardiac myosin inhibitor for the treatment of HCM; and omecamtiv mecarbil, a potential treatment across the continuum of care in heart failure with severely reduced ejection fraction. In addition, the company is involved in developing and Ulacamten, a novel, selective, oral, and small molecule cardiac myosin inhibitor designed to reduce the hypercontractility associated with heart failure with preserved ejection fraction in Phase 1 clinical trials; and CK-089, a fast skeletal muscle troponin activator in Phase 1 clinical trials. Cytokinetics, Incorporated was incorporated in 1997 and is headquartered in South San Francisco, California.

United States · www.cytokinetics.com

Risk Metrics

Beta vs SPX0.74
Corr SPX0.22
Annual vol54.8%
Annual ret+23.3%
Sharpe0.43
Max DD-49.1%

Window: 504 trading days (504 obs)

Analyst Coverage

Mean PT$104.00
High / Low$146.00 / $69.00
Median$103.00
Analysts19
Strong Buy7
Buy11
Hold3
Sell0
Strong Sell0

Recent rating actions

2026-05-07Wells Fargo→ Overweight
2026-05-06Stifel→ Buy
2026-05-06RBC Capital→ Outperform
2026-05-06Morgan Stanley→ Overweight
2026-05-05Needham→ Buy
2026-04-10Wells Fargo→ Overweight

Material Events

DateEvent8-K
2026-08-13Other Material Eventread
2026-08-06Earnings Release, Exhibitsread
2026-05-27Shareholder Voteread
2026-05-08Other Material Event, Exhibitsread
2026-05-05Other Material Event, Exhibitsread
2026-05-05Earnings Release, Exhibitsread
2026-02-24Earnings Release, Exhibitsread
2026-02-17Other Material Eventread
2025-12-19Other Material Eventread
2025-12-12Other Material Eventread
2025-11-14Officer / Director Changeread
2025-11-05Earnings Release, Exhibitsread

Insider Trades

DateInsiderRoleActionSharesValue
2026-08-10Blum Robert IPresident & CEOOption exercise7.50K$79.50K
2026-08-10Blum Robert IPresident & CEOSell7.50K$575.70K
2026-07-30Callos AndrewEVP, Chief Commercial OffOption exercise14.00K$325.64K
2026-07-30Callos AndrewEVP, Chief Commercial OffSell14.00K$1.12M
2026-07-27Blum Robert IPresident & CEOSell7.50K$606.52K
2026-07-27Blum Robert IPresident & CEOOption exercise7.50K$79.50K
2026-07-21Malik Fady IbrahamEVP Research & DevelopmenOption exercise3.50K$27.30K
2026-07-21Malik Fady IbrahamEVP Research & DevelopmenSell3.50K$282.06K
2026-07-15Daly James MGrant151$12.48K
2026-07-15WIERENGA WENDELLGrant75$6.20K

Flow & Concentration

Insider 180d net-$2.58M
Insider buys / sells0 / 4
Insider biasSellers
13F holders0
Top-5 share0.0%
HHI0 (—)

SEC Filings

DateFormDoc
2026-08-138-Kview
2026-08-104view
2026-08-0610-Qview
2026-08-068-Kview
2026-07-304view
2026-07-274view
2026-07-234view
2026-07-164view
2026-07-164view
2026-07-164view
2026-07-164view
2026-07-164view
2026-07-164view
2026-07-144view
2026-07-074view

The Long Run

FY 2011–2025 · 15 years

LineLatestCAGRTrend
Revenue$18.47M-14.7%
Operating income-$612.26M—
Net income-$526.24M—
Cash from ops-$395.89M+6.3%

Indices

S&P MidCap 400

Recent Sessions

DateOpenHighLowCloseVol
Sep 25$65.66$65.95$64.44$64.661.60M
Sep 24$65.37$66.47$64.89$65.661.84M
Sep 23$67.02$67.39$64.73$65.812.05M
Sep 22$68.07$69.56$67.48$67.592.39M
Sep 21$69.30$69.50$67.35$67.561.60M

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