Inside the research
Cytokinetics, Incorporated
CYTK Research profile · latest available data
Price overview
$64.66
▼ -1.00 (-1.5%)
| 52w hi | $87.26 |
|---|---|
| 52w lo | $47.83 |
| Vol | 1.60M |
| As of | 25 Sep 2026 |
The Verdict
Our score -0.45
| Short | -0.11 |
|---|---|
| Medium | -0.42 |
| Long | -1.16 |
computed 2026-09-27
Key fundamentals
Cytokinetics, Incorporated
Healthcare · Biotechnology
| Market cap | $8.99B |
|---|---|
| Enterprise value | $9.25B |
| Forward P/E | -14.52x |
| EV / EBITDA | -13.30x |
| P / S (ttm) | 132.84x |
| Profit margin | 0.0% |
| Revenue growth | -57.1% |
Layer Breakdown
| Layer | Raw | Contribution |
|---|---|---|
| Fundamental | -0.31 | |
| Sector | +0.08 | |
| Technical | -0.17 | |
| Earnings | +0.00 | |
| Sentiment | +0.00 |
macro × 1.00 · 2026-09-27
Business overview
Cytokinetics, Incorporated, a biopharmaceutical company, focuses on discovering, developing, and commercializing novel muscle activators and muscle inhibitors as potential treatments for debilitating diseases in the United States. The company markets MYQORZO, a novel, oral, and small molecule cardiac myosin inhibitor for the treatment of symptomatic oHCM. It also develops Aficamten, a novel, oral, and small molecule cardiac myosin inhibitor for the treatment of HCM; and omecamtiv mecarbil, a potential treatment across the continuum of care in heart failure with severely reduced ejection fraction. In addition, the company is involved in developing and Ulacamten, a novel, selective, oral, and small molecule cardiac myosin inhibitor designed to reduce the hypercontractility associated with heart failure with preserved ejection fraction in Phase 1 clinical trials; and CK-089, a fast skeletal muscle troponin activator in Phase 1 clinical trials. Cytokinetics, Incorporated was incorporated in 1997 and is headquartered in South San Francisco, California.
Risk Metrics
| Beta vs SPX | 0.74 |
|---|---|
| Corr SPX | 0.22 |
| Annual vol | 54.8% |
| Annual ret | +23.3% |
| Sharpe | 0.43 |
| Max DD | -49.1% |
Window: 504 trading days (504 obs)
Analyst Coverage
| Mean PT | $104.00 |
|---|---|
| High / Low | $146.00 / $69.00 |
| Median | $103.00 |
| Analysts | 19 |
| Strong Buy | 7 | |
|---|---|---|
| Buy | 11 | |
| Hold | 3 | |
| Sell | 0 | |
| Strong Sell | 0 |
Recent rating actions
| 2026-05-07 | Wells Fargo | → Overweight |
| 2026-05-06 | Stifel | → Buy |
| 2026-05-06 | RBC Capital | → Outperform |
| 2026-05-06 | Morgan Stanley | → Overweight |
| 2026-05-05 | Needham | → Buy |
| 2026-04-10 | Wells Fargo | → Overweight |
Material Events
| Date | Event | 8-K |
|---|---|---|
| 2026-08-13 | Other Material Event | read |
| 2026-08-06 | Earnings Release, Exhibits | read |
| 2026-05-27 | Shareholder Vote | read |
| 2026-05-08 | Other Material Event, Exhibits | read |
| 2026-05-05 | Other Material Event, Exhibits | read |
| 2026-05-05 | Earnings Release, Exhibits | read |
| 2026-02-24 | Earnings Release, Exhibits | read |
| 2026-02-17 | Other Material Event | read |
| 2025-12-19 | Other Material Event | read |
| 2025-12-12 | Other Material Event | read |
| 2025-11-14 | Officer / Director Change | read |
| 2025-11-05 | Earnings Release, Exhibits | read |
Insider Trades
| Date | Insider | Role | Action | Shares | Value |
|---|---|---|---|---|---|
| 2026-08-10 | Blum Robert I | President & CEO | Option exercise | 7.50K | $79.50K |
| 2026-08-10 | Blum Robert I | President & CEO | Sell | 7.50K | $575.70K |
| 2026-07-30 | Callos Andrew | EVP, Chief Commercial Off | Option exercise | 14.00K | $325.64K |
| 2026-07-30 | Callos Andrew | EVP, Chief Commercial Off | Sell | 14.00K | $1.12M |
| 2026-07-27 | Blum Robert I | President & CEO | Sell | 7.50K | $606.52K |
| 2026-07-27 | Blum Robert I | President & CEO | Option exercise | 7.50K | $79.50K |
| 2026-07-21 | Malik Fady Ibraham | EVP Research & Developmen | Option exercise | 3.50K | $27.30K |
| 2026-07-21 | Malik Fady Ibraham | EVP Research & Developmen | Sell | 3.50K | $282.06K |
| 2026-07-15 | Daly James M | Grant | 151 | $12.48K | |
| 2026-07-15 | WIERENGA WENDELL | Grant | 75 | $6.20K |
Flow & Concentration
| Insider 180d net | -$2.58M |
|---|---|
| Insider buys / sells | 0 / 4 |
| Insider bias | Sellers |
| 13F holders | 0 |
| Top-5 share | 0.0% |
| HHI | 0 (—) |
SEC Filings
The Long Run
FY 2011–2025 · 15 years
| Line | Latest | CAGR | Trend |
|---|---|---|---|
| Revenue | $18.47M | -14.7% | |
| Operating income | -$612.26M | — | |
| Net income | -$526.24M | — | |
| Cash from ops | -$395.89M | +6.3% |
Indices
Recent Sessions
| Date | Open | High | Low | Close | Vol |
|---|---|---|---|---|---|
| Sep 25 | $65.66 | $65.95 | $64.44 | $64.66 | 1.60M |
| Sep 24 | $65.37 | $66.47 | $64.89 | $65.66 | 1.84M |
| Sep 23 | $67.02 | $67.39 | $64.73 | $65.81 | 2.05M |
| Sep 22 | $68.07 | $69.56 | $67.48 | $67.59 | 2.39M |
| Sep 21 | $69.30 | $69.50 | $67.35 | $67.56 | 1.60M |
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