The Bid & Ask

Quotations, Dispatches, and the Daily Tape

Thursday, August 13, 2026

Subject of the day

KRYS

Concerning the House

Krystal Biotech, Inc., a commercial-stage biotechnology company, discovers, develops, manufactures, and commercializes genetic medicines to treat diseases with high unmet medical needs in the United States. The company commercializes VYJUVEK (beremagene geperpavec-svdt, or B-VEC) for the treatment of dystrophic epidermolysis bullosa (DEB). It also develops KB803 for ocular complications of dystrophic epidermolysis bullosa; KB801 for neurotrophic keratitis; KB407, which is in Phase 1 clinical trials for treating cystic fibrosis; KB111 for Hailey-Hailey disease; KB707 for solid tumors; KB304 for dynamic wrinkles; KB707 that is in Phase 1/2 clinical trials for the treatment of anti-PD-1 relapsed/refractory; KB408, which is in Phase 1 clinical trials for treating Alpha-1 antitrypsin deficiency; and KB301 that is in Phase 2 clinical trials for treating aesthetic skin conditions, as well as in open label study with ophthalmic B-VEC for treating for ocular complications of deb. Krystal Biotech, Inc. was founded in 2016 and is headquartered in Pittsburgh, Pennsylvania.

United States · www.krystalbio.com

The Long Run

FY 2017–2025 · 7 years

LineLatestCAGRTrend
Revenue$389.13M+33.9%
Operating income$65.75M
Net income$204.83M
Cash from ops-$88.80M
Quotation

$328.34

-4.52 (-1.4%)

52w hi$378.15
52w lo$137.46
Vol132.06K
As ofAug 13
The Verdict

Hold

Our score +0.13

Short-0.10
Medium+0.24
Long+0.36

computed 2026-08-13

By the Numbers

Krystal Biotech, Inc.

Healthcare · Biotechnology

Market cap$9.72B
Enterprise value$9.02B
Trailing P/E41.09x
Forward P/E34.10x
EV / EBITDA45.24x
P / S (ttm)22.06x
Profit margin54.8%
Return on equity20.1%
Revenue growth+24.1%
Earnings growth+38.8%
Debt / equity0.65
Risk Metrics
Beta vs SPX0.90
Corr SPX0.35
Annual vol42.2%
Annual ret+39.2%
Sharpe0.93
Max DD-39.5%

Window: 504 trading days (504 obs)

Layer Breakdown
LayerRawContribution
Fundamental+0.27
Sector+0.12
Technical+0.00
Earnings+0.00
Sentiment+0.00

macro × 1.00 · 2026-08-13

Recent Sessions
DateOpenHighLowCloseVol
Aug 13$334.00$334.88$327.34$328.34132.06K
Aug 12$326.95$334.21$325.00$332.86161.90K
Aug 11$333.30$336.28$324.34140.76K
Aug 10$324.54$332.73$324.54$331.59151.90K
Aug 7$326.34$329.00$320.34$326.45160.00K